Computer Aided Drug Design (CADD) from A to Z

Course Overview

This course provides a comprehensive overview of Computer Aided Drug Design (CADD) from A to Z. It is designed to equip learners with the basics and concepts of drug discovery, and to enable them to design drugs from scratch. The course covers theoretical and practical illustrations for all concepts of drug discovery, including sources of lead compound in drug discovery, methods of lead optimization, improvement of drug physiochemical properties, design of drug agonist or antagonist, drug latentiation (prodrug), therapeutic aspects of drug-receptor interaction, structural (steric) features and pharmacological activity, classification of drug active ingredients, quantitative structural activity relationship QSAR, methods used to correlate physicochemical parameters and biological activity, molecular modeling in drug design, and docking using MOE program. Upon completion of the course, participants will have a better understanding of the relationships between physico-chemical properties of drugs and their biological activities, as well as the types of interactions between drugs and receptors. They will also be familiar with modern techniques in the field of drug design, such as computer-based methods of quantitative structural activity relationship QSAR and molecular graphics.